Principles and technologies for generating genomic information for ecological, biomedical and biotechnological applications. Technologies will be introduced progressively, from DNA to RNA to protein to whole cell systems. The integration of biology, chemistry, engineering and computational sciences will be stressed. Topics include: Technology for the High-throughput Sequencing, Methods for annotating genomes, characterizing functional genes, Gene Expression, Comparative Genomics, Population Genomics, Proteomic Technologies and Systems Biology.